The 5 Best CBD Creams for Aches and Pains in 2024

Cannabidiol (CBD) cream for pain may help relieve muscle aches and tension, although research is still ongoing. We have found and tried some of the best CBD creams for pain available to buy online.
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A quick look at some of the best CBD creams for pain
Best overall: CBDfx Muscle and Joint Cream, Cooling Formula | Skip to review
CBDfx Muscle and Joint Cream, Cooling Formula
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Best for muscle soreness: Level Select Sports CBD Cream, Level 2 Mint | Skip to review
Level Select Sports CBD Cream, Level 2 Mint
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Best for targeted relief: R&R Full Spectrum CBD Cream | Skip to review
R&R Full Spectrum CBD Cream
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Best for back pain: PlusCBD Pain Relief Penetrating Cream | Skip to review
PlusCBD Pain Relief Penetrating Cream
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Best for rapid relief: Soul CBD Rapid Relief Cream | Skip to review
Soul CBD Rapid Relief Cream
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Benefits of CBD for pain
CBD binds to molecules in the body, blocking some protein receptors and inhibiting certain enzymes and acids that play a role in pain and inflammation.
binds to molecules
Researchers have found that certain compounds in the cannabis plant may have beneficial effects, including:
Researchers
Alleviating pain: Studies show that in adults with neuropathic pain, cannabis-based medication may help achieve more than 50% pain relief compared with a placebo. An additional 2021 study shows that CBD may also be effective in reducing pain due to fibromyalgia.
neuropathic pain
more than 50%
2021 study
fibromyalgia
Reducing spasms: A 2022 study suggests that a combination of CBD and tetrahydrocannabinol (THC) may help reduce pain and muscle spasticity in people with multiple sclerosis (MS).
2022 study
muscle spasticity
multiple sclerosis (MS)
Relaxing muscles: The cannabis plant contains two anti-inflammatory agents that aid muscle relaxation and may enhance muscle recovery after exercise. In a 2023 clinical trial, athletes ages 18 to 65 years received two post-exercise doses of a formula containing CBD, cannabigerol, and several other ingredients. After 72 hours, the athletes experienced less muscle discomfort and stiffness and a higher range of muscle motion.
2023 clinical trial
cannabigerol
Reducing inflammation: Studies involving the administration of CBD in dogs, horses, and rats at different doses have shown positive anti-inflammatory and antioxidant effects. However, researchers need to conduct more human studies to support these findings.
Studies
antioxidant
Learn more about CBD for pain management.
CBD for pain management
Visit our dedicated hub for more research-backed information and in-depth resources on CBD.
CBD
Best CBD creams for pain
Medical News Today has tested some of the products below. Reviewers may have received some products from the manufacturers for free, which does not influence their review. All opinions are the reviewers’ own.
CBDfx Muscle and Joint Cream, Cooling Formula

CBD type: broad-spectrum
broad-spectrum
CBD potency: 1,000 mg per 1.7-fl oz bottle, 3,000 mg per 1.7-fl oz bottle
COA: available online
available online
Third-party tested: yes
Use code “HEALTHLINE” for 20% off.
$79.99 AT CBDFX
*Price may vary.
According to CBDfx, this cream soothes aches and pains in a person’s deep tissues and joints.
This cream contains two anti-inflammatory ingredients for pain relief: white willow bark and caffeine. Additionally, it features menthol for a cooling effect, which may provide pain relief.
caffeine
The company uses hemp from growers in the United States. The People for the Ethical Treatment of Animals (PETA) organization has certified that this product is cruelty-free and vegan-friendly.
People for the Ethical Treatment of Animals (PETA)
vegan
The cream also undergoes testing at a third-party laboratory. The company displays its Certificate of Analysis (COA) on its website.
Certificate of Analysis (COA)

Read our review of CBDfx and learn more about the best CBD products for joint pain.
review of CBDfx
best CBD products for joint pain
Subscriptions and savings
With a subscription, customers can save 25% and receive free shipping. People can use third-party companies such as Sezzle and Klarna to spread the cost. Orders over $75 come with free shipping.

Use code “HEALTHLINE” for 20% off.

“The bottle came in a nice box with all the ingredients listed and warnings, etc. on it. The bottle itself has a cream pump for dispensing the cream, which I found useful for dosing.
“The cream is soft, smooth, and did not leave greasy residue on my skin. It absorbed well and quickly.
“I found that the menthol was very cooling immediately, and my pain was reduced (or numbed, maybe), by the cream. At 3,000 milligrams (mg) CBD per 50 milliliter (mL) bottle, I find the potency very effective.
“It smells a bit minty, as you would expect from a product that contains menthol. But, the scent goes away after rubbing the cream in to your skin, so you don’t walk around smelling strongly of the scent – I’ve encountered that with other CBD creams.
“I would recommend this to anyone looking for a simple and effective way to use CBD cream for pain.”
— Christy Snyder, Healthline editor
“The bottle came in a nice box with all the ingredients listed and warnings, etc. on it. The bottle itself has a cream pump for dispensing the cream, which I found useful for dosing.
“The cream is soft, smooth, and did not leave greasy residue on my skin. It absorbed well and quickly.
“I found that the menthol was very cooling immediately, and my pain was reduced (or numbed, maybe), by the cream. At 3,000 milligrams (mg) CBD per 50 milliliter (mL) bottle, I find the potency very effective.
“It smells a bit minty, as you would expect from a product that contains menthol. But, the scent goes away after rubbing the cream in to your skin, so you don’t walk around smelling strongly of the scent – I’ve encountered that with other CBD creams.
“I would recommend this to anyone looking for a simple and effective way to use CBD cream for pain.”
— Christy Snyder, Healthline editor
contains two anti-inflammatory ingredients
company says it is fast-acting
also contains menthol to promote a cooling effect
reviewers note pain relief is short-term only
fairly expensive compared with some competitors
CBDfx does not ship to all 50 U.S. states
contains two anti-inflammatory ingredients
company says it is fast-acting
also contains menthol to promote a cooling effect
reviewers note pain relief is short-term only
fairly expensive compared with some competitors
CBDfx does not ship to all 50 U.S. states
Returns: returns within 60 days
Shipping: free shipping on orders over $75
Returns: returns within 60 days
Shipping: free shipping on orders over $75
Level Select Sports CBD Cream, Level 2 Mint

CBD type: broad-spectrum
broad-spectrum
CBD potency: 1,200 mg per 3-oz jar
COA: available online
available online
Third-party tested: yes
Use code “HEALTH40” for 40% off.
$40.00 AT LEVEL SELECT
*Price may vary.
Level Select CBD’s cruelty-free sports cream contains broad-spectrum CBD. Its Level 2 product is for people with higher levels of muscle soreness, which may be useful for active people and athletes.
This cream contains anti-inflammatory menthol for cooling relief and absorbs fast into the skin. This may mean it provides quick pain relief and does not leave a sticky residue on the skin.
It is free from THC, so it is suitable for people undergoing regular drug testing. Level Select CBD claims that it does not test ingredients on animals.
Learn about the best CBD salves for athletes.
best CBD salves for athletes
People can view this cream’s COA here.
here
Subscriptions and savings
People can choose from three subscription options offering deliveries every 1, 2, or 3 months to save money on their orders. If a person subscribes to deliveries of one product, they can save 30%. Subscriptions for two products offer 35% off.
There is also a 30-day money-back guarantee.
Use code “HEALTH40” for 40% off.
the website states that the product has no traces of THC
there are three strengths for a person to choose from
the company claims the formula is fast-absorbing
the company offers free shipping
product only available in a 3-oz tub
limited reviews on the website
the website states that the product has no traces of THC
there are three strengths for a person to choose from
the company claims the formula is fast-absorbing
the company offers free shipping
product only available in a 3-oz tub
limited reviews on the website
Returns: full refund within 30 days
Shipping: free shipping
Returns: full refund within 30 days
Shipping: free shipping
R&R Full Spectrum CBD Cream

CBD type: full-spectrum
full-spectrum
CBD potency: 1,000 mg per 2.5-fl oz tube, 2,500 mg per 2.5-fl oz tube, 5,000 mg per 2.5-fl oz tube
COA: available online
available online
Third-party tested: yes
$55.00 AT R&R CBD
*Price may vary.
This full-spectrum CBD pain cream is available in 1,000 mg, 2,500 mg, and 5,000 mg and comes in a 2.5 fluid ounce (fl oz) tube. The company claims the formula is anti-inflammatory and may be suitable for localized pain.
It contains plant-based oils and extracts to moisturize and protect the skin, including:
shea butter
shea butter
jojoba seed oil
jojoba seed oil
arnica extract
sunflower seed oil
calendula extract
avocado oil
avocado oil
aloe vera gel
aloe vera gel
Its arnica montana flower extract is useful in the treatment of bruising. Aloe vera may also help reduce pain, according to 2019 research.
is useful
2019 research

People can view this cream’s COA on the company’s website.
company’s website
Subscriptions and savings
There are various subscription options that help people save 20% on this product. Buyers can choose to receive deliveries every 30, 60, or 90 days and buy in packs of 1 to 3 tubes.
There is also free shipping available for orders over $60 and a 60-day money-back guarantee.
there is a 60-day money back guarantee
company states the formula absorbs easily
three strength options
fairly expensive compared with competitors
contains trace amounts of THC
only one tube size is available
there is a 60-day money back guarantee
company states the formula absorbs easily
three strength options
fairly expensive compared with competitors
contains trace amounts of THC
only one tube size is available
Returns: full refund within 60 days
Shipping: free shipping on orders over $60
Veteran-Founded
Returns: full refund within 60 days
Shipping: free shipping on orders over $60
Veteran-Founded
PlusCBD Pain Relief Penetrating Cream

CBD type: full-spectrum
full-spectrum
CBD potency: 1,000 mg per bottle
COA: available online
available online
Third-party tested: yes
Use code “healthline40” for 40% off.
$39.99 AT PLUSCBD
*Price may vary.
PlusCBD offers this vegan and gluten-free pain relief muscle cream that contains full-spectrum CBD. The company recommends this cream for neck and backache strains.
In addition to CBD, the cream contains cooling menthol and warming camphor. Research from 2023 states that these ingredients may be effective in treating pain.
Research from 2023
The manufacturer states that people can apply a thin layer of this cream to the skin area they want to treat for targeted pain relief.
PlusCBD also writes that the cream is free of genetically modified organisms (GMOs), pesticides, and sulfates. People can view this cream’s COA on the company’s website.
company’s website
Subscriptions and savings
People can save 25% on deliveries every 30, 60, or 90 days.
“[I used it] as needed for joint pain. It felt a little greasy, but the cooling sensation was very therapeutic.
“This was great for deeper joint pain. I had some knee pain that almost melted away instantly after application. Great for pain, if just a little messy. Though not ideal for hand pain, since application to the hands directly may result in accidental contact with the eyes and subsequent irritation.
“[I would recommend it for] anyone looking for nonpharmaceutical relief for moderate pain.”
– Connor Rice, SEO content project manager
“[I used it] as needed for joint pain. It felt a little greasy, but the cooling sensation was very therapeutic.
“This was great for deeper joint pain. I had some knee pain that almost melted away instantly after application. Great for pain, if just a little messy. Though not ideal for hand pain, since application to the hands directly may result in accidental contact with the eyes and subsequent irritation.
“[I would recommend it for] anyone looking for nonpharmaceutical relief for moderate pain.”
– Connor Rice, SEO content project manager
provides a dual warming and cooling effect
the company recommends it for neck and back pain and strains
unfragranced, so may be ideal for those with sensitive skin
only one choice of strength
limited reviews on the company website
provides a dual warming and cooling effect
the company recommends it for neck and back pain and strains
unfragranced, so may be ideal for those with sensitive skin
only one choice of strength
limited reviews on the company website
Returns: full refund within 90 days
Shipping: shipping calculated at checkout
Returns: full refund within 90 days
Shipping: shipping calculated at checkout
Soul CBD Rapid Relief Cream

CBD type: isolate
isolate
CBD potency: 1,500 mg per 3.4-fl oz bottle
COA: available on product page
Third-party tested: yes
Use code “HEALTHLINE30” for 30% off.
$75.00 AT SOUL CBD
*Price may vary.
Soul CBD Rapid Relief Cream does not contain THC, which means those avoiding this ingredient may prefer it. It is still quite potent, with 1,500 mg of CBD per container. Menthol creates a cooling effect, which some may find soothing.
The brand claims this cream acts fast and may benefit those looking to target chronic pain at specific sites.
Soul CBD advises applying the cream to the affected area and massaging it into the skin.
The product contains no artificial ingredients. People can view the COA for this product on Soul CBD’s website.
Soul CBD’s website.
Subscriptions and savings
People can get 15% off the regular price when they subscribe. Delivery is every 4 weeks. Soul CBD also offers a rewards program where you can redeem points for coupons.
“I used this CBD cream on a tight hip and lower back for some sciatic pain.
“The product comes in a nice bottle with a dispenser pump, so it was easy to apply. It’s not greasy or sticky and rubs in nicely.
“It smells strongly of menthol. Like toothpaste, really. The scent lingered for a while, just a heads up for anyone who is sensitive to strong scents.
“I noticed a cooling sensation from the menthol and a slight reduction of pain.
“[I would recommend this], though there are stronger CBD creams out there. I’d recommend this as the best THC-free topical option.”
– Christy Snyder, Healthline editor
“I used this CBD cream on a tight hip and lower back for some sciatic pain.
“The product comes in a nice bottle with a dispenser pump, so it was easy to apply. It’s not greasy or sticky and rubs in nicely.
“It smells strongly of menthol. Like toothpaste, really. The scent lingered for a while, just a heads up for anyone who is sensitive to strong scents.
“I noticed a cooling sensation from the menthol and a slight reduction of pain.
“[I would recommend this], though there are stronger CBD creams out there. I’d recommend this as the best THC-free topical option.”
– Christy Snyder, Healthline editor
Soul CBD claims the product works rapidly
15% discount with subscription
this product is free from THC
price is on the higher end at $74 (before discounts)
reviews report a strong scent
shorter return window than other brands
Soul CBD claims the product works rapidly
15% discount with subscription
this product is free from THC
price is on the higher end at $74 (before discounts)
reviews report a strong scent
shorter return window than other brands
Returns: returns within 14 days
Shipping: free shipping on orders over $75
Returns: returns within 14 days
Shipping: free shipping on orders over $75
Comparing CBD creams for pain
The following table compares the CBD creams in this article on CBD type, main features, and price.
CBDfx
Level Select
R&R
PlusCBD
Soul CBD
How we choose CBD creams for pain
Medical News Today chooses CBD creams for pain that fit the following criteria:
We selected these CBD creams for pain based on criteria we think are good indicators of safety, quality, and transparency.
As a part of our vetting process, we consider:
the product’s composition, ingredients, and overall quality
any third-party certifications
the company’s reputation and business practices
any lab test results
marketing claims
We also look at the following factors:
Pain relief: Where possible, MNT selects CBD creams that brands recommend for managing pain.
Ingredients: MNT chooses creams containing safe, high quality, and clearly labeled ingredients. Brands should also confirm that the product is free from pesticides, heavy metals, and mold.
Dosage: MNT selects creams that clearly state the CBD dosage and THC content.
Serving size: MNT chooses CBD creams with recommended dosages and usage instructions.
How to choose a CBD cream for pain
People may wish to consider several factors before purchasing a CBD cream for pain. These factors include:
Third-party tests: A person should only purchase CBD products from companies with COAs available for their products. These certificates verify that the products’ ingredient lists are correct and present in the amounts and potencies the company states.
Ingredients: Buyers should ensure the hemp in a CBD cream is natural and U.S.-grown. Sometimes, it is possible to get CBD creams containing certified organic hemp. Individuals with allergies should ensure all the ingredients are suitable for them. Those with sensitive skin may wish to avoid creams that have fragrances or irritants known to them.
CBD spectrum: CBD creams for pain often contain full- or broad-spectrum CBD, but some products use CBD isolate. People should consider the THC content in full-spectrum CBD, especially if they have regular drug tests. Learn more about CBD spectrums to find out which may be best in a CBD cream for pain.
about CBD spectrums
Potency: CBD potency refers to the strength of the product. CBD creams with more milligrams per application will be more potent than those with lower values. Those experiencing higher pain levels may appreciate a higher potency product, but CBD creams should not replace medical care to treat severe pain.
Ease of application: CBD creams for pain may not always be convenient to use, especially if a person wants to manage their pain on the go. Products in tubes may be easier to apply to specific areas, while creams in tubs may work for people using them over larger areas.
What type of CBD is best?
CBD creams are a good choice for people who want an easily portable product that provides targeted relief. As many creams contain cooling menthol or warming camphor, people will notice an almost immediate effect.
However, other CBD options include:
CBD oils and tinctures: These oral products come with droppers that make it easy to measure a dose. Oils are a good choice for overall wellness but may not be as effective for targeted relief. Oils and tinctures can have some of the highest amounts of CBD per dose.
CBD gummies: Like oils, these products may assist with overall wellness. They are easily transportable, often have flavorings and sugar to help mask the taste of hemp, and come in a range of strengths.
Other CBD topicals: If creams are not suitable, many companies offer other topical products that contain CBD, such as bath bombs, face and foot masks, and more. These are good choices for people who do not need regular CBD and want to have it as part of their beauty and wellness routine.
Risks of CBD
As the inclusion of CBD into health products is a relatively recent development, there is a lack of scientific research examining its long-term risks. The Food and Drug Administration (FDA) has only approved one CBD product, Epidiolex, a prescription medication for rare types of epilepsy. As such, no other CBD products have FDA approval — including CBD creams for pain.
Epidiolex
People can apply CBD cream to their skin like any other topical product, but it is important to follow the instructions on the product packaging.
People should also perform a patch test before using a new CBD cream on their skin. If they experience a reaction to the product, they should stop using it and contact a doctor. Reactions can include skin itching, redness, or inflammation.
patch test
inflammation
Anyone taking medicines and considering using a CBD cream should also consult a doctor or qualified CBD clinician. These professionals can advise whether CBD will interact with the medication.
Frequently asked questions about CBD cream for pain
CBDfx’s Muscle and Joint Cream is one of the strongest over-the-counter CBD creams available online. It is available in 1,000 and 3,000 mg and may help soothe aches and pains in deep-tissue joints. However, a cream this strong may not be suitable for people who are new to CBD.
CBDfx’s Muscle and Joint Cream
CBDfx’s Muscle and Joint Cream is one of the strongest over-the-counter CBD creams available online. It is available in 1,000 and 3,000 mg and may help soothe aches and pains in deep-tissue joints. However, a cream this strong may not be suitable for people who are new to CBD.
CBDfx’s Muscle and Joint Cream
Research from 2023 suggests CBD may help manage chronic pain symptoms in adults. However, CBD products may help relieve pain temporarily rather than eliminating it.
Research from 2023
Research from 2023 suggests CBD may help manage chronic pain symptoms in adults. However, CBD products may help relieve pain temporarily rather than eliminating it.
Research from 2023
Research from 2022 states that topical CBD may help reduce inflammatory conditions, such as eczema. A 2019 paper suggests that CBD has anti-inflammatory benefits, making it potentially beneficial for reducing inflammation.
Research from 2022
2019 paper
Research from 2022 states that topical CBD may help reduce inflammatory conditions, such as eczema. A 2019 paper suggests that CBD has anti-inflammatory benefits, making it potentially beneficial for reducing inflammation.
Research from 2022
2019 paper

In some cases, CBD cream may cause skin irritation, including discoloration, itching, or a rash.

According to the FDA, some individuals can experience side effects from using CBD, including:
FDA
changes in alertness, including drowsiness or sleepiness
gastrointestinal distress, including diarrhea or decreased appetite
mood changes, including irritability or agitation
However, this relates to ingestible CBD products.
Forms of CBD a person applies topically, including creams and ointments, do not enter the bloodstream.
Forms of CBD a person applies topically, including creams and ointments, do not enter the bloodstream.
The effective level of CBD for pain depends on the intensity and type of pain the person experiences. Therefore, there is no one-fits-all rule.
A 2022 review notes that the effectiveness of the CBD a person takes depends on its THC-to-CBD ratio. Researchers found that products with a higher THC-to-CBD ratio may be more effective at managing pain than products with a higher CBD-to-THC ratio.
2022 review
The effective level of CBD for pain depends on the intensity and type of pain the person experiences. Therefore, there is no one-fits-all rule.
A 2022 review notes that the effectiveness of the CBD a person takes depends on its THC-to-CBD ratio. Researchers found that products with a higher THC-to-CBD ratio may be more effective at managing pain than products with a higher CBD-to-THC ratio.
2022 review
A 2018 review found that full-spectrum CBD products may be most effective for treating inflammation and joint pain.
2018 review
For people wanting to avoid THC, broad-spectrum or CBD isolate products are preferable.
More research is required to determine the best dose or format of CBD for treating inflammation and joint pain.
A 2018 review found that full-spectrum CBD products may be most effective for treating inflammation and joint pain.
2018 review
For people wanting to avoid THC, broad-spectrum or CBD isolate products are preferable.
More research is required to determine the best dose or format of CBD for treating inflammation and joint pain.
Summary
CBD creams are products a person applies to their skin. They may help reduce pain and inflammation.
Although CBD creams may provide some pain relief, people should seek guidance from a healthcare professional first to assess the underlying cause of their pain and receive medical treatment, if necessary.
People should also consult a qualified healthcare professional or pharmacist if they intend to use CBD products alongside prescription or nonprescription medications to reduce the risk of drug interactions and side effects.
Is CBD legal?The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3% THC federally legal. However, CBD products containing more than 0.3% THC still fall under the legal definition of marijuana, making them federally illegal but legal under some state laws. Be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.
state laws

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